Implant to be tested in Burlington for opioid use disorder

Posted On Dec 31 2020 by

first_imgMaster Trainer Dr Matt Torrington of the UCLA Integrated Substance Abuse Programs works closely with qualified healthcare providers to teach them best practices for insertion and removal of the Probuphine implant, a new treatment option for opioid use disorder. Braeburn photo.Vermont Business Magazine Braeburn Pharmaceuticals(link is external) announced today that healthcare provider training and certification for Probuphine will take place on July 29 and 30 in Burlington. Approved by the Food and Drug Administration (FDA)(link is external) on May 26, 2016, Probuphine is the first implant for the maintenance treatment of opioid dependence in patients who have sustained clinical stability on low-to-moderate doses of buprenorphine, specifically 8 mg or less per day.  Healthcare providers in the Burlington area can register for Probuphine training here(link is external) or by calling 1-866-397-8939.Opioid use disorder is a chronic brain disease and one of the fastest growing public health epidemics in America. Last year in Vermont, 83 people died from an opioid overdose. Research has shown that opioid use disorder is best treated with a combination of medication and psychosocial support. The majority of individuals with opioid use disorder cannot sustain recovery without long-term outpatient medical treatment.”Braeburn is committed to making Probuphine available to patients in the Burlington area and across the country as soon as possible, which is why we’re conducting training sessions so quickly after receiving FDA approval for Probuphine,” said President and CEO Behshad Sheldon, Braeburn Pharmaceuticals. “We look forward to educating qualified healthcare providers in Burlington on July 29 and 30 on best practices for insertion and removal of Probuphine, the only treatment for opioid dependence that delivers medicine for up to six months. To date, 2,236 physicians from all 50 states and Puerto Rico have been certified to provide Probuphine to their patients.”Probuphine will not be distributed by pharmacies; patients can only receive the treatment from certified healthcare providers who have been specially trained to insert the implants just under the skin of the inside of the upper arm through an in-office procedure.This weekend’s training sessions for Probuphine in Burlington are part of a series of 262 that Braeburn is conducting across 55 cities this summer.About ProbuphineProbuphine is the only FDA approved long-acting buprenorphine treatment for opioid dependence. Probuphine delivers buprenorphine continuously for six months using Titan Pharmaceuticals’ (NASDAQ: TTNP) ProNeura™ technology. Probuphine is placed under the skin of the upper arm during an outpatient office procedure and is removed in a similar manner.For More Information on ProbuphineProbuphine is now available in all 50 U.S. States. Patients interested in Probuphine should visit the Probuphine Healthcare Provider Locator to find a trained and certified provider near them:www.probuphinerems.com/probuphine-locator(link is external).Probuphine is not distributed by pharmacies. Qualified healthcare providers can register for Probuphine training at www.probuphineREMS.com(link is external) or by calling 1-866-397-8939.WARNING: IMPLANT MIGRATION, PROTRUSION, EXPULSION and NERVE DAMAGE ASSOCIATED WITH INSERTION and REMOVALRisk Associated with Insertion and RemovalInsertion and removal of PROBUPHINE are associated with the risk of implant migration, protrusion, expulsion resulting from the procedure. Rare but serious complications including nerve damage and migration resulting in embolism and death may result from improper insertion of drug implants inserted in the upper arm. Additional complications may include local migration, protrusion and expulsion. Incomplete insertions or infections may lead to protrusion or expulsion.Because of the risks associated with insertion and removal, PROBUPHINE is available only through a restricted program called the PROBUPHINE REMS Program. All Healthcare Providers must successfully complete a live training program on the insertion and removal procedures and become certified, prior to performing insertions or prescribing PROBUPHINE implants. Patients must be monitored to ensure that PROBUPHINE is removed by a healthcare provider certified to perform insertions.Please see additional Important Safety Information in the Package Insert that can be found at probuphine.com or by following this link http://probuphinerems.com/wp-content/uploads/2016/02/final-approved-pi.pdf(link is external).About Opioid Use Disorder and Buprenorphine Opioid use disorder is a chronic brain disease and one of the fastest growing public health epidemics in America. In the U.S., 2.5 million people struggle with opioid addiction and, according to the Centers for Disease Control, 78 people die each day from the disease. There is a growing body of evidence that opioid addiction is not a choice or a moral failing, but the result of genetic predisposition combined with environmental factors. Nonetheless, individuals struggling with this disease continue to be stigmatized. Research has also shown that opioid use disorder is best treated with a combination of medication and psychosocial support. The majority of individuals with opioid addiction cannot sustain recovery without long-term outpatient medical treatment.Buprenorphine is a partial opioid agonist, which may help individuals to stop opioid use without experiencing withdrawal symptoms. Before FDA approval of Probuphine, buprenorphine was only available in oral form which must be taken daily.About Braeburn PharmaceuticalsBraeburn Pharmaceuticals, an Apple Tree Partners company, is a pharmaceutical company focused on long-acting therapeutic treatment options that are essential to improving patient outcomes and facilitating recovery in neurological and psychiatric disorders, which are often complicated by stigma and present significant public health challenges. Braeburn’s commercial product, Probuphine® (buprenorphine) implant was approved by the FDA in May 2016. Braeburn’s investigational product pipeline consists of long-acting implantable and injectable therapies for serious neurological and psychiatric disorders, including opioid addiction, pain, and schizophrenia. Braeburn’s pipeline products are at various stages of clinical development and include CAM2038, weekly and monthly subcutaneous injection depot formulations of buprenorphine, being investigated in opioid addiction and pain; a risperidone six-month implant being investigated in schizophrenia; and a novel molecule, ATI-9242, is being investigated for treatment of schizophrenia. More information on Braeburn, can be found atwww.braeburnpharmaceuticals.com(link is external).SOURCE BURLINGTON, Vt., July 26, 2016 /PRNewswire/ — Braeburn Pharmaceuticals, Inc.last_img read more


Facebook and Narcissism

Posted On Dec 9 2020 by

first_imgThe New York Times:A Times article recently debated whether young people are more narcissistic than previous generations, mentioning Facebook as a possible factor. And a University of Michigan study, published in June, seems to support this theory.Are social media like Facebook turning us into narcissists?Read the discussion: The New York Times More of our Members in the Media >last_img


One City’s Ambitious Plan To Ease Overcrowded Trains? Pay Riders

Posted On Dec 8 2020 by

first_imgFast Company:BART, the regional transportation system in the San Francisco Bay Area, has a new strategy to help cope with commute-hour congestion that’s packing train platforms and cars to the gills: BART Perks, a rewards program that uses cold hard cash to make off-peak travel more enticing. BART’s leadership is betting that this unconventional short-term solution will be a big enough patch until longer term plans come to fruition.As cities grapple with ways to better manage their transit systems, BART is using a psychology-fueled strategy to solve the age-old problem of getting people to work efficiently and on time. If the grand experiment proves successful, it sets a benchmark for other municipalities struggling to alleviate commute-hour congestion on trains. Will it work?Read the whole story: Fast Company More of our Members in the Media >last_img read more


John Griffin Steps Down From Indy Racing League

Posted On Oct 20 2020 by

first_imgINDIANAPOLIS — Indy Racing League Vice President of Public Relations John Griffin has submitted his resignation, effective Dec. 18. AdvertisementClick Here to Read MoreAdvertisement “John has been a valued part of our organization and he will be missed,” said Terry Angstadt, president of the commercial division of the Indy Racing League. “His creativity and passion for the sport brought publicity for the IZOD IndyCar Series to a whole new level. We wish him the best of luck.” Griffin joined the Indy Racing League as vice president in 2002, overseeing all aspects of the IZOD IndyCar Series and Firestone Indy Lights public and media relations program as well as strategic communication. During his tenure, Griffin developed and implemented public relations strategies for several historic events including the unification of open-wheel racing, Danica Patrick’s first win and the series IZOD entitlement announcement earlier this month. “I appreciate my time here at the Indy Racing League where I have made many great friends and want to thank Terry (Angstadt) and Brian (Barnhart) for the opportunity,” said Griffin. “I really think the time is right for me to entertain a new challenge, particularly something that would allow me more quality time with my kids.” Before joining the Indy Racing League, Griffin worked for NASCAR with his professional career also including stops with World Cup USA 1994 and the Major Indoor Soccer League. Advertisement A replacement for Griffin has not been selected.last_img read more


New Mexico COVID-19 Cases Now At 686

Posted On Oct 19 2020 by

first_imgSTATE News:SANTA FE – New Mexico state health officials today announced 62 additional positive tests for COVID-19.Los Alamos County remain at 2 confirmed case.Per the New Mexico Department of Health, the most recent cases are:16 new cases in Bernalillo County1 new case in Chaves County1 new case in Doña Ana County2 new cases in Grant County4 new cases in McKinley County25 new cases in San Juan County11 new cases in Sandoval County2 new cases in Santa Fe CountyToday’s announced cases include additional positive tests from the La Vida Llena long-term care facility in Albuquerque, where one additional resident and two additional staff members have now tested positive for COVID-19.The number of deaths in the state related to COVID-19 remains 12.Including the above newly reported cases, New Mexico has now had a total of 686 positive tests for COVID-19:Bernalillo County: 262Catron County: 1Chaves County: 14Cibola County: 14Curry County: 6Doña Ana County: 30Eddy County: 4Grant County: 3Lea County: 2Lincoln County: 1Los Alamos County: 2McKinley County: 44Otero County: 3Rio Arriba County: 6Roosevelt County: 1Sandoval County: 114San Juan County: 83San Miguel County: 1Santa Fe County: 64Socorro County: 5Taos County: 13Torrance County: 6Valencia County: 7County totals are subject to change upon further investigation and determination of residency of individuals positive for COVID-19.As of today, there are 48 individuals hospitalized in New Mexico for COVID-19. This number may include individuals who tested positive for COVID-19 out of state but are currently hospitalized in New Mexico. This number does not include New Mexicans who tested positive for COVID-19 and may have been transferred to a hospital out of state.As of today, there are 133 COVID-19 cases designated as having recovered by the New Mexico Department of Health.The Department of Health has detected community spread and is investigating cases with no known exposure. The agency reports that given the infectious nature of the virus it is likely other residents are infected but yet to be tested or confirmed positive. To that end, all New Mexicans have been instructed to stay home except for outings absolutely necessary for health, safety and welfare. These additional restrictions have been enacted to aggressively minimize person-to-person contact and ensure spread is mitigated. All businesses except those deemed essential have been ordered to close. New Mexicans are strongly urged to limit travel to only what is necessary for health, safety and welfare.The New Mexico Department of Health has active investigations into the positive patients, which includes contact-tracing and swabs of symptomatic individuals who have had contact with the positive cases.Every New Mexican must work together to stem the spread of COVID-19. Stay home.New Mexicans who report symptoms of COVID-19 infection, such as fever, cough, or shortness of breath, should call their health care provider or the NMDOH COVID-19 hotline immediately (1-855-600-3453).Thanks to increased statewide testing capacity, the following people may now be considered for COVID-19 testing: Asymptomatic people who are close contacts or household members of New Mexico residents who have already tested positive for the coronavirus;Asymptomatic residents in nursing homes;Asymptomatic people in congregant settings such as homeless shelters, group homes, detention centers; andSymptomatic people displaying the COVID-19 symptoms of cough, fever or shortness of breath. New Mexicans who have non-health-related questions or concerns can also call 833-551-0518 or visit newmexico.gov, which is being updated regularly as a one-stop source for information for families, workers and others affected by and seeking more information about COVID-19.​The state Department of Health will update its dedicated COVID-19 webpage with additional tests as the state lab provides results.last_img read more


Home Depot fires 70-year-old Army veteran for confronting shoplifters

Posted On Sep 28 2020 by

first_img Do you see a typo or an error? Let us know. Author: AP Home Depot fires 70-year-old Army veteran for confronting shoplifters Home Depot and Lowe’s will start requiring customers to wear masks Recommended Dresser recalled by Home Depot due to tip over risk, entrapment hazard PEARLAND, Texas (CBS/AP) A 70-year-old Army veteran has been fired from a Houston-area Home Depot after trying to stop suspected shoplifters from taking thousands of dollars’ worth of merchandise.KTRK-TV in Houston reports that Jim Tinney says he was fired last month from the store in Pearland.Tinney says he was trained to not confront shoplifters and knows he violated company policy, but that his military training just kicked in when he noticed three men attempting to steal tools. He threw a paint roller extension pole toward the suspects’ feet. The men escaped.The Home Depot said in a statement that only trained company security personnel can pursue and engage shoplifters, citing the safety of customers and associates.A Pearland Police Department spokesman says he has no information on the shoplifting case. SHARE Published: July 18, 2017 4:26 AM EDT Updated: July 18, 2017 8:26 AM EDT last_img read more


Video hearings pilot will uphold ‘majesty of a physical courtroom’, HMCTS pledges

Posted On Sep 28 2020 by

first_imgFully video courtrooms will be piloted with members of the public for the first time, the government has announced, kicking off with tax appeals this spring.HM Courts & Tribunals Service says video hearings will save people time and money spent travelling to court and waiting. People with health problems that make it difficult for them to attend court, will also benefit, the announcement said. Participants will need a computer and a webcam so they can log in from a location of their choice. The judge will sit in a courtroom.HMCTS says it is ‘working closely with the judiciary to ensure the majesty of a physical courtroom will be upheld’. The judge will decide whether to hold a video hearing. Private conversations will be possible before the hearing begins. The hearing format and process will remain the same.The Gazette has been told that the ‘small scale’ pilot will hold up to 24 cases. Two members of the judiciary will hear any pilot case. The hearings will take about one-and-a-half hours. Appropriate hearings will considered from across England. Justice minister Lucy Frazer said today: ‘We are spending £1bn on transforming and modernising the justice system. Video hearings have the potential to improve access to justice and speed up cases. This pilot will provide important information – together with an increasing body of evidence from other countries – to drive innovation to make the wider system quicker, smarter and much more user-friendly.’HMCTS says video technology is already used in criminal courts to allow some victims and witnesses to give evidence without coming face-to-face with the accused. They cite a 97-year-old victim of an aggravated burglary and a witness to a gang murder as examples.Former magistrate Penelope Gibbs, director of Transform Justice, which campaigns for a fair and open justice system, told the Gazette that research on video hearings for defendants and immigration detainees suggests that being on video leads to worse outcomes, including more imprisonment and a greater number of decisions to deny bail.A survey conducted by the charity last year showed that over half of respondents thought appearing on video made it more difficult for defendants to understand what was going on in their hearings and to participate. Nearly three-quarters said defendants who had no legal representation were disadvantaged by appearing on video.Gibbs said today: ‘I hope HMCTS will do a full evaluation of outcomes in this pilot so we know whether virtual hearings help or hinder access to justice.’The Law Society said people lodging tax appeals are likely to be well educated, and not financially or technologically excluded. The cases are also likely to be reasonably straightforward. Joe Egan, president, said: ‘This makes these cases a good environment to test out the principles and technology for holding fully virtual hearings. However, it must be remembered that more complex cases and more vulnerable participants are likely to give rise to extra challenges that may not be addressed in this pilot.’We look forward to learning with HMCTS the lessons to be drawn from the pilot, and to discussing with them the issues that will need to be considered before rolling out this technology further.’last_img read more


Photo gallery: Parkway vs. West Ouachita Division II soccer quarterfinals

Posted On Sep 20 2020 by

first_imgImages from Saturday’s Division II girls soccer quarterfinal playoff game between Parkway and West Ouachita at Centenary College Top Expat InsuranceExpat Living in Hong Kong without Health Insurance?Top Expat Insurance|SponsoredSponsoredUndoNews gadgetThis watch takes the whole country by storm! it’s price? Ridiculous!News gadget|SponsoredSponsoredUndoTheTopFiveVPNThe Secret Netflix Doesn’t Want You To Know To Unblock RestrictionsTheTopFiveVPN|SponsoredSponsoredUndoPerfect-Dating.comAre You Ready to Meet Cool Guys in Tung Chung?Perfect-Dating.com|SponsoredSponsoredUndoTheTopFiveVPNThe Trick Netflix Doesn’t Want You To Know To Unlock RestrictionsTheTopFiveVPN|SponsoredSponsoredUndoCelebsland.com9 Celebrity Before-And-After Plastic Surgery DisastersCelebsland.com|SponsoredSponsoredUndolast_img read more


From Italy: ‘Summit’ took place between Liverpool’s Klopp and Raiola to…

Posted On Sep 18 2020 by

first_imgAccording to the Italian website on Wednesday afternoon, the Reds’ hunt for a new goalkeeper to help fill the gap left by the most likely departing Simon Mignolet has taken them to the young Italian, which means Mino Raiola is involved.The Dutch super agent has been trying to get his client away from Milan for a while, and it appears Liverpool could be one of his solutions, as TMW report a ‘summit’ between Jürgen Klopp and Raiola took place a few days ago to discuss the matter.Donnarumma wasn’t the only topic of conversation between the two, either, as the pair also discussed the future of Justin Kluivert, currently at Ajax and linked with a move away from Holland this summer.Embed from Getty ImagesAs things stand, no offer has been made for the goalkeeper, but obviously that could change at any moment.Considering the faith Klopp has put in Loris Karius this season, it seems unlikely that another first-team goalkeeper would come in despite all the January rumours, but perhaps he only saw the German as the lesser of two evils.Unlikely, though.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksTrending TodayForge of Empires – Free Online GameIf You Like to Play, this City-Building Game is a Must-Have. No Install.Forge of Empires – Free Online GameUndo聽多多 Hearmore.asia1969年前出生的香港居民現可免費試戴頂尖的歐洲助聽器聽多多 Hearmore.asiaUndo美術寶1對1香港媽媽們注意了,速來領取適合4-12歲孩子的繪畫課,手慢無美術寶1對1UndoTheTopFiveVPNEnjoy Netflix Now Without Any RestrictionsTheTopFiveVPNUndoSingles50Hong Kong: A 40+ Dating Site That Actually Works!Singles50UndoLoans | Search AdsNeed a loan? Search hereLoans | Search AdsUndoCoworking Space | Search AdsThe cost of shared office in Hong Kong might surprise youCoworking Space | Search AdsUndoSmart Tech TrendOver 55? You Have to Try Those Revolutionary Glasses!Smart Tech TrendUndo熱門話題生髮率無敵高!96%的禿頭都獲得改善!←這會不會長太多?熱門話題Undo If (and it’s a big one) TuttoMercatoWeb’s latest exclusive is to be believed, then Liverpool are very much interested in AC Milan’s Gianluigi Donnarumma.last_img read more


Even my 92-year old mother had sage advice for Flacco

Posted On Aug 30 2020 by

first_imgMy mother met Joe Flacco last night. She doesn’t move so great these days but she still knows how to give solid advice.It’s the same advice she gave me in the 1970’s in Dundalk.Enjoy…last_img